For prevention and treatment of Crop Fungus. Prevents/Treats Blackhead Disease in poultry! For prevention and treatment of Crop Fungus. Treats Blackhead Disease in poultry! Acidified Copper Sulfate is used as an antimicrobial to sanitize water lines and waterers for poultry. It can also be used as a preventative and treatment for blackhead (histomoniasis) in turkeys and canker (trichomonosis) in chickens. Acidified Copper Sulfate is supplied as a 1-lb powder. To use, dilute 1 pound into 2 gallons of water. Then add this stock solution by mixing 1 ounce into 1 gallon of drinking water. To treat disease, give the final dilution as a sole source of drinking water for 7-10 days. Dump and replace the final dilution drinking water every 24 hours during the entire treatment period.